Upper Tract Urothelial Carcinoma

The EAU upper tract urothelial carcinoma (UTUC) pathway — from clinical suspicion through CT-urography, ureteroscopy and urine cytology to diagnosis (with germline/Lynch testing), CT staging and risk stratification, and risk-directed treatment: kidney-sparing surgery for low-risk disease, radical nephroureterectomy with bladder-cuff (± lymphadenectomy, adjuvant chemo/IO) for high-risk and cN+, metastatic systemic therapy (EVP / platinum chemo ± IO / avelumab maintenance / later lines), and risk-based follow-up. Switch between the visual Pathway map and the phase-by-phase Explorer.